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You are here: Home > Research > Sen-itiroh Hakomori, M.D., Ph.D. >
Recent Publications
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- Miura Y, Kainuma M, Jiang H, Velasco H, Vogt PK, Hakomori S. Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3) ganglioside. Proc Natl Acad Sci USA 101(46): 16204-9. 2004.
- Suzuki E, Handa K, Toledo MS, Hakomori S. Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert. Proc Natl Acad Sci USA 101(41): 14788-93. 2004.
- Mitsuzuka K, Handa K, Satoh M, Arai Y, Hakomori S. A specific microdomain ("glycosynapse 3") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of α3β1 integrin with CD9. J Biol Chem 80(42): 35545-53. 2005.
- Toledo MS, Suzuki E, Handa K, Hakomori S. Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor. J Biol Chem 280(16): 16227-16234. 2005.
- Yoon S, Nakayama K, Takahashi N, Yagi H, Utkina N, Wang HY, Kato K, Hakomori S. Interaction of N-linked glycans, having multivalent GlcNAc termini, with GM3 ganglioside. Glycoconj J 23(9): 639-649. 2006.
- Yoon S, Nakayama K, Hikita T, Handa K, Hakomori S. Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor. Proc Natl Acad Sci USA 103(50): 18987-18991. 2006.
- Todeschini AR, Dos Santos JN, Handa K, Hakomori S. Ganglioside GM2/ tetraspanin CD82 complex inhibits Met activation, and its cross-talk with integrins: Basis for control of cell motility through glycosynapse. J Biol Chem Papers In Press, published online January 10, 2007;
doi:10.1074/jbc.M611407200. 2007.
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