Research Programs

Publications

All Publications and Patents for Dr. David Galas can be found through this link to Google Scholar which will open in a new window.

Selected Major Publications for Dr. David Galas

  • Branscomb, E. W. and Galas, D. J., “Progressive Decrease in Protein Synthesis Accuracy Induced by Streptomycin in E. coli,” Nature, 254:161-163 (1975).  (reprinted in Benchmark Papers in Genetics Series, Genes, Proteins and Cellular Aging, ed. R. Holliday, van Nostrand Reinhold Co., New York, (1976).
  • Galas, D. J. and Schmitz, A., “DNAase Footprinting: A Simple Method for the Detection of Protein-DNA Binding Specificity,” Nucleic Acids Res., 5:3157-3170 (1978).
  • Schmitz, A. and Galas, D. J., “The Interaction of RNA Polymerase and lac Repressor with the lac Control Region,” Nucleic Acids Res., 6:111-137 (1979).
  • Galas, D. J. and Chandler, M., “On the Molecular Mechanisms of Transposition,” Proc. Nat. Acad. Sci., 78:4858-4862 (1981).
  • Waterman, M., Arratia, R. and Galas, D., “Pattern Recognition in Several Sequences: Consensus and Alignment,” Bull. Math. Biol., 46:515-527 (1984).
  • Galas, D., Eggert, M. and Waterman, M., “Rigorous Pattern Recognition Methods for DNA Sequences: Analysis of Promoter Sequences for E. coli,” J. Mol. Biol., 186:117-128 (1985).
  • Prentki, P., Chandler, M. and Galas, D., “E. coli Integration Host Factor Bends the DNA at the Ends of IS1 and in an Insertion Hotspot with Multiple IHF Binding Sites,” EMBO Journ., 6:2479-2487, (1987).
  • Galas, D. and Chandler, M.,  “Bacterial Insertion Sequences” (review) Chapter 4 in Mobile DNA, pp. 109-162, American Society for Microbiology, Washington, D.C., (1989)
  • Collins, F. and Galas, D. J., “A New Five-year Plan for the U. S. Human Genome Project,” Science, 262:43-46, (1993)
  • Levy-Lahad E., Wasco W., Poorkaj P., Ramano D., Oshima J., Pettingell W., Yu C., Jondro P., Schmidt S., Wang K., Crowley A., Fu YH., Guenette S., Galas D., Nemens E., Wijsman E., Bird T., Schellenberg G., and Tanzi R., “Candidate Gene for the Chromosone 1 Familial Alzheimer’s Disease Locus,” Science, 269:973-977, (1995).
  • Galas, D. J., “New Genetic Tools: Their Roles in Drug Discovery and Development,” International Journal of Pharmaceutical Medicine, 12:13-18 (1998).
  • Brunkow, M., Gardner, J., Van Ness, J., Paeper, B., Kovacevich, B., Proll, S., Skonier, J., Zhao, L., Sabo, P.J., Fu, Y., Alisch, R., Gillett, L., Colbert, T., Tacconi, P., Galas, D., Hamersma, H., Beighton, P., and Mulligan, J., “Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot-Containing Protein,” American Journal of Human Genetics, 68:577-589 (2001).
  • Galas, D.J., “The Invention of Footprinting”, Trends in Biochemical Sciences, 26:690-693 (2001).
  • Chung, F., Dewey, T.G., Lu Liang, and Galas, D. J., “Duplication Models and Biological Networks,”Journal of Computational Biology, 10(5):667-687 (2003).
  • Van Ness, J., Van Ness, L., and Galas, D.J., “Isothermal Reactions for the Amplification of Oligonucleotides,” Proc. Nat. Acad. Sci. USA, 100:4504-4509 (2003).
  • Wang, K., Zhang, S., Marzolf, B., Troisch, P., Brightman, A., Hu, Z., Hood, L.E., and Galas, D.J., “Circulating microRNAs, potential biomarkers for drug-induced liver injury,” PNAS, 106(11):4402-4407 (2009).
  • Carter, G.W., Galitski, T. and Galas, D.J., “Maximal Extraction of Biological Information from Genetic Interaction Data,” PLoS Computational Biology, 5(4):e1000347 (2009).
  • Wang, K., Zhang, S., Weber, J., Baxter, D., and Galas, D.J., “Mammalian cells in culture actively export specific microRNAs,” Nucleic Acids Research, 38(20):7248-7259 (2010).
  • Roach, J.C., Glusman, G., Smit, A.F.A., Huff, C.D., Hubley, R., Shannon, P.T., Rowen, L., Pant, K.P., Goodman, N., Bamshad, M., Shendure, J., Drmanac, R., Jorde, L.B., Hood, L., and Galas, D.J., “Analysis of Genetic Inheritance in a Family Quartet by Whole Genome Sequencing," Science, 328(5978):636-639 (2010).
  • Wang, K., Li, H., Yuan, Y., Etheridge, A., Huang, D., Wilmes, P., and Galas, D.J., “The Complex Exogenous RNA Spectra in Human Plasma: an Interface with Human Gut Microbiome?”, PLoS ONE, 7(12):e51009. doi:10.1371/journal.pone.0051009 (2012).
  • Galas DJ, Sakhanenko NA, Skupin A, Ignac T., "Describing the Complexity of Systems: Multivariable "Set Complexity" and the Information Basis of Systems Biology", J. Comp. Biol., PMID: 24377753 [Epub ahead of print] (2013).

Recent publications

2015

  • Ghosal, A., Upadhyaya, B.B., Fritz, J.V., Heintz-Buschart, A., Wang, K., Desai, M., Dilimulati, Y., Huang, D., Baumuratov, A., Galas, D.J., Wilmes, P., “The extracellular RNA complement of Escherichia coli and its immunostimulatory properties”, MicrobiologyOpen, doi: 10.1002/mbo3.235 (2015).
  • Viollet, L., Glusman, G., Murphy, K.J., Newcomb, T.M., Reyna, S.P., Sweney, M., Nelson, B., Andermann, F., Andermann, E., Acsadi, G., Barbano, R.L., Brown, C., Brunkow, M.E., Chugani, H.T., Cheyette, S.R., Collins, A., DeBrosse, S.D., Galas, D., Friedman, J., Hood, L., Huff, C., Jorde, L.B., King, M.D., LaSalle, B., Leventer, R.J., Lewelt, A.J., Massart, M.B., Mérida, M.R. 2nd, Ptáček, L.J., Roach, J.C., Rust, R.S., Renault, F., Sanger, T.D., Sotero de Menezes, M.A., Tennyson, R., Uldall, P., Zhang, Y., Zupanc, M., Xin, W., Silver, K., Swoboda, K.J., “Alternating Hemiplegia of Childhood: Retrospective Genetic Study and Genotype-Phenotype Correlations in 187 subjects from the US AHCF registry”, PLoS One, May 21;10(5):e0127045. doi: 10.1371/journal.pone.0127045. eCollection (2015).
  • Sakhanenko, N.A. and Galas, D.J., “Biological data analysis as an information theory problem: Multivariable dependence measures and the Shadows algorithm”, Journal of Computational Biology, Sep 3 [Epub ahead of print].
  • Argyropoulos, C., Wang, K., Bernardo, J., Ellis, D., Orchard, T., Galas, D.J., Johnson, J.P., “Urinary MicroRNA profiling predicts the development of microalbuminuria in patients with Type 1 Diabetes”, J. Clin. Med., Jul; 4(7): 1498–1517; doi:10.3390/jcm4071498 (2015).
  • Subramanian, S.L., Kitchen, R.R., Alexander, R., Carter, B.S., Cheung, K.H., Laurent, L.C., Pico, A., Roberts, L.R., Roth, M.E., Rozowsky, J.S., Su, A.I., Gerstein, M.B., Milosavljevic, A., “Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies”, J. Extracell. Vesicles, Aug 28;4:27497. doi: 10.3402/jev.v4.27497. eCollection (2015).

exRNA Consortium (click for related press release)

  • Quinn, J.F., Patel, T., Wong, D., Das, S., Freedman, J.E., Laurent, L.C., Carter, B.S., Hochberg, F., Van Keuren-Jensen, K., Huentelman, M., Spetzler, R., Kalani, M.Y., Arango, J., Adelson, P.D., Weiner, H.L., Gandhi, R., Goilav, B., Putterman, C., Saugstad, J.A., “Extracellular RNAs: development as biomarkers of human disease”, J. Extracell. Vesicles, Aug 28;4:27495. doi: 10.3402/jev.v4.27495. eCollection (2015).
  • Patton, J.G., Franklin, J.L., Weaver, A.M., Vickers, K., Zhang, B., Coffey, R.J., Ansel, K.M., Blelloch, R., Goga, A., Huang, B., L'Etoille, N., Raffai, R.L., Lai, C.P., Krichevsky, A.M., Mateescu, B., Greiner, V.J., Hunter, C., Voinnet, O., McManus, M.T., “Biogenesis, delivery, and function of extracellular RNA”, J. Extracell. Vesicles, Aug 28;4:27494. doi: 10.3402/jev.v4.27494. eCollection (2015).
  • Ainsztein, A,M., Brooks, P.J., Dugan, V.G., Ganguly, A., Guo, M., Howcroft, T.K., Kelley, C.A., Kuo, L.S., Labosky, P.A., Lenzi, R., McKie, G.A., Mohla, S., Procaccini, D., Reilly, M., Satterlee, J.S., Srinivas, P.R., Church, E.S., Sutherland, M., Tagle, D.A., Tucker, J.M., Venkatachalam, S., “The NIH Extracellular RNA Communication Consortium”, J. Extracell. Vesicles, Aug 28;4:27493. doi: 10.3402/jev.v4.27493. eCollection (2015).

in press

  • Ameziane, N., May, P., Haitjema, A., van de Vrugt, H., Van Rossum – Fikkert, S., Ristic, D., Williams, G., Balk, J., Rockx, D., Li, H., Rooimans, M., Oostra, A., Velleuer, E., Dietrich, R., Bleijerveld, O., Altelaar, M., Meijers-Heijboer, H., Joenje, H., Glusman, G., Roach, J., Hood, L., Galas, D.J., Wyman, C., Balling, R., den dunnen, J., De Winter, J., Kanaar, R., Gelinas, R., and Dorsman, J., "A novel Fanconi anemia subtype associated with a dominant-negative mutation in RAD51", Nature Communications (in press, 2015).
     
  • Stittrich, A., Ashworth, J., Shi, M., Robinson, M., Mauldin, D., Brunkow, M., Biswas, S., Kim, J-M., Kwon, K-S., Jung, J., Galas, D.J., Serikawa, K., Duerr, R., Guthery, S., Peschon, J., Hood, L., Roach, J., and Glusman, G., "Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals", Human Genome Variation (in press, 2015).

2014

  • Wilkening S, Lin G, Fritsch ES, Tekkedil MM, Anders S, Kuehn R, Nguyen M, Aiyar RS, Proctor M, Sakhanenko NA, Galas DJ, Gagneur J, Deutschbauer A, Steinmetz LM., “An Evaluation of High Throughput Approaches to QTL Mapping in Saccharomyces cerevisiae”, Genetics, 196(3):853-65 (2014).
  • Galas DJ, Sakhanenko NA, Skupin A, Ignac T., “Describing the Complexity of Systems: Multivariable "Set Complexity" and the Information Basis of Systems Biology”, J. Comp. Biol., 21(2):118-40 (2014).
  • Cho et al., "Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder", PNAS, 111(8):3188-93 (2014).
  • Ignac, T., Skupin, A., Sakhanenko, N., Galas, D.J., ”Discovering pair-wise genetic interactions: An information theory-based approach”, PLoS One, 9(3):e92310 (2014).
  • Galas, D.J., Wilmes, P., Wang, K., “RNA in Circulation: Sources and Functions of Extracellular Exogenous RNA in the Blood”, Chapter in Encyclopedia of Metagenomics. Springer Science+Business Media, New York (2014).
  • Hao Hu, Jared Roach, Hilary Coon, Stephen Guthery, Sean Tavtigian, Shankaracharya, Wilfred Wu, Jinchuan Xing, Shuoguo Wang, Gustavo Glusman, Robert Hubley, Hong Li, Vidu Garg, Barry Moore, Alisha Holloway, Leroy Hood, Katie S Pollard, David J Galas, Deepak Srivastava, Martin G Reese, Lynn Jorde, Mark Yandell, Chad Huff, “A unified test of linkage analysis and rare-variant association (pVAAST)”, Nature Biotechnology, doi:10.1038/nbt.2895 (2014).
  • Galas, D.J., Sakhanenko, N., Keller, B., “On the Symmetries and Dualities of Information Measures: Lattices, Conditionals and Complex Systems”, Entropy, 16, 1-x manuscripts; doi:10.3390/e160x000x (2014).
  • Schneider, J. et al. “Molecular and Clinical Evidence for an ARMC5 Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations are Associated with both Primary Macronodular Adrenal Hyperplasia and Meningioma”, Journal of Clinical Endocrinology & Metabolism, Oct 3:jc20142648 (2014).
  • Krishna, A., Biryukov, M., Trefois, C., Antony, P.M.A., Hussong, R., Lin, J., Heinäniemi, M., Koeglsberger, S.,    Boyd, O., van den Berg, B.H.J., Linke, D., Huang, D., Wang, K., Tholey, A., Schneider, R., Galas, D.J., May, P., Balling, R., “Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease”, BMC Genomics, 15:1154 (2014).
  • Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J.R.,. de Kovel, C.G.F., Thiele, H., Konrad, K., Kawalia. A., Toliat, M., Sander, T., Rüschendorf, F., Caliebe, A., Nagel, I., Kohl, B., Kecskés, A., Jacmin, M., Hardies, K., Weckhuysen, S., Riesch. E., Dorn, T., Brilstra, E.H., Baulac, S., Møller, R.S., Hjalgrim, H., Koeleman, B., Jurkat-Rott, K., Lehman- Horn, F., Roach, J.C., Glusman, G., Hood, L., Galas, D.J., Martin, B., de Witte, P. A.M., Biskup, S., De Jonghe, P., Helbig, I., Balling, R., Nürnberg, P., Crawford, A.D., Esguerra, C.V., Weber, Y.G., Lerche, H. “Mutations in STX1B encoding a key presynaptic protein cause fever-associated epilepsy syndromes” (letter), Nature Genetics, 46(12):1327-32 (2014).

2013

  • Wang, K., Yuan, Y., Li, H., Cho, JH, Huang, D., Gray, L., Qin, S., Galas, D., “The spectrum of circulating RNA, a window into systems toxicology”, Toxicol Sci, 132(2):478-92 (2013).
  • Etheridge, A., Gomes, Clarissa P. C., Pereira, R.W., Galas, D.J., and Wang, K., “The complexity, function, and applications of RNA in circulation”, Front. Genet., doi: 10.3389/fgene.2013.00115 (2013).
  • Shannon, P.T., Grimes, M., Kutlu, B., Bot, J.J., and Galas, D.J.,”RCytoscape: Tools for Exploratory Network Analysis”, BMC Bioinformatics, Jul 9;14(1):217. [Epub ahead of print] (2013).
  • Galas, D.J., Sakhanenko, N.A., and Keller, B., “On Lattices and the Dualities of Information Measures”, arXiv preprint arXiv:1308.0047 (2013).
  • Patra, B., Kon, Y., Yadav, G., Sevold, A.W.,  Frumkin, J.P., Vallabhajosyula, R.R., Hintze, A., Østman, B., Schossau, J., Bhan, A., Marzolf, B., Tamashiro, J.K., Kaur, A., Baliga, N.S., Grayhack, E.J., Adami, C., Galas, D.J., Raval, A., Phizicky, E.M., Ray, A., “A genome wide dosage suppressor network reveals genetic robustness and a novel mechanism for Huntington's disease”, arXiv preprint arXiv:1311.2554 (2013).
  • Wilkening S, Lin G, Fritsch ES, Tekkedil MM, Anders S, Kuehn R, Nguyen M, Aiyar RS, Proctor M, Sakhanenko NA, Galas DJ, Gagneur J, Deutschbauer A, Steinmetz LM., “An Evaluation of High Throughput   Approaches to QTL Mapping in Saccharomyces cerevisiae”, Genetics, PMID: 24374355 [Epub ahead of print] (2013).
  • Galas DJ, Sakhanenko NA, Skupin A, Ignac T., “Describing the Complexity of Systems: Multivariable "Set Complexity" and the Information Basis of Systems Biology”, J. Comp. Biol., PMID: 24377753 [Epub ahead of print] (2013).

2012

  • Ignac, T.M., Sakhanenko, N.A., Skupin, A, and Galas, D.J., “New methods for finding associations in large data sets: generalizing the maximal information coefficient (MIC),” Proceedings of the 9th International Workshop on Computational Systems Biology (WCSB; 2012).
  • Qin S., Zhou Y., Lok A.S., Tsodikov A., Yan X., Gray L., Yuan M., Moritz R.L., Galas, D., Omenn G.S., and Hood L., “SRM targeted proteomics in search for biomarkers of HCV-induced progression of fibrosis to cirrhosis in HALT-C patients,”  Proteomics, 12:1244-52 (2012).
  • Wang, K., Yuan, Y., Cho, J-H., McClarty, S., Baxter, D., and Galas, D.J., “Comparing the microRNA spectrum between serum and plasma,” PLoS ONE, 7(7):e41561 (2012).
  • Ignac, T.M., Sakhanenko, N.A., Galas, D.J., “Relations Between the Set-Complexity of a Graph and its Structure,” EURASIP Journal on Bioinformatics and Systems Biology, 2012:13 doi:10.1186/1687-4153-2012 (2012).
  • Sakhanenko, N. and Galas, D.J., “Probabilistic logic methods and some applications to biology and medicine,” J. Comp Biol., 19(3):316-336 (2012).
  • Wang, K., Li, H., Yuan, Y., Etheridge, A., Huang, D., Wilmes, P., and Galas, D.J., “The Complex Exogenous RNA Spectra in Human Plasma: an Interface with Human Gut Microbiome?”, PLoS ONE, 7(12):e51009. doi:10.1371/journal.pone.0051009 (2012).
  • Argyropoulos, C., Wang, K., McClarty, S., Huang, D., Bernardo, J., Ellis, D., Orchard, T., Galas, D., Johnson, J., “Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes”, PLoS ONE, 8(1):e54662. doi: 10.1371/journal.pone.0054662 [Epub ahead of print] (2013).

2011

  • Vêncio, E.F.,  Pascal, L.E., Page, L.S., Denyer, G., Wang, A.J., Ruohola-Baker, H., Zhang, S., Wang, K., Galas, D.J., and Liu, A.Y., “Embryonal carcinoma cell induction of miRNA and mRNA changes in co-cultured prostate stromal fibromuscular cells,” Journal of Cellular Physiology , 226(6):1479–1488 (2011).
  • Bousquet, J., Anto, J.M., Sterk, P.J., Adcock, I.M., Chung, K.F., Roca, J., Agusti, A., Brightling, C., Cambon-Thomsen, A., Cesario, A., Abdelhak, S., Antonarakis, S.E., Avignon, A., Ballabio, A., Baraldi, E., Baranov, A., Bieber, T., Bockaert, J., Brahmachari, S., Brambilla, C., Bringer, J., Dauzat, M., Ernberg, I., Fabbri, L., Froguel, P., Galas, D.J., Gojobori, T., Hunter, P., Jorgensen, C., Kauffmann, F., Kourilsky, P., Kowalski, M.L., Lancet, D., Le Pen, C., Mallet, J., Mayosi, B., Mercier, J., Metspalu, A., Nadeau, J.H., Ninot, G., Noble, D., Oztürk, M., Palkonen, S., Prefaut, C., Rabe, K., Renard, E., Roberts, R.G., Samolinski, B., Schünemann, H.J., Simon, H-U, Bento Soares, M., Superti-Furga, G., Tegner, J., Verjovski-Almeida, S., Wellstead, P., Wolkenhauer, O., Wouter, E., Balling, R., Brookes, A.J., Charron, Dominique, Pison, C., Chen, Z., Hood, L. and Auffray, C., “Systems medicine and integrated care to combat chronic noncommunicable diseases,” Genome Medicine, 3(43): doi:10.1186/gm259 (2011).
  • Gelinas, R., Chesler, E.J., Vasconcelos, D., Miller, D.R., Yuan, Y., Wang, K., and Galas, D.J., “A genetic approach to the prediction of drug side effects: bleomycin induces concordant phenotypes in mice of the collaborative cross,” Pharmacogenomics and Personalized Medicine, 4(1):35 – 45 (2011).
  • Cho, J-H., Wang, K., and Galas, D.J., “An integrative approach to inferring biologically meaningful gene modules,” BMC Systems Biology, 5:117 (2011).
  • Sakhanenko, N. and Galas, D.J., “Complexity of Networks I: The Set-complexity of Binary Graphs,”Complexity, 17:51-64 (2011).
  • Roach, J.C., Glusman, G., Hubley, R., Montsaroff, S.Z., Holloway, A.K., Srivastava, D., Garg, V., Pollard, K.S., Galas, D.J., Hood, L., and Smit, A.F.A., “Chromosomal Haplotypes by Genetic Phasing of Human Families,” Amer. Journ. Human Genetics, 89(3):382–397 (2011).
  • Pedroza, M., Schneider, D., Karmouty-Quintana, H., Coote, J., Shaw, S., Corrigan, R., Molina, J., Alcorn, J., Galas, D.J., Gelinas, R. and Blackburn, M., “Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury,” PLoS ONE, 6(7):e22667 (2011).
  • Ignac, T.M., Sakhanenko, N.A., and Galas, D.J., “Relation Between the Set-Complexity of a Graph and its Structure”, Proceedings of the 8th International Workshop on Computational Systems Biology (WCSB; 2011).
  • Lee, M., Cho, J., Galas, D.J., and Wang, K., “The systems biology of Neurofibromatosis type 1 –critical roles for microRNA,” Experimental Neurology, 235(2):464-468 (2011).
  • Ignac, T.M., Sakhanenko, N. and Galas, D.J., “Complexity of Networks II: The Set-complexity of a Class of Edge-colored Graphs,” Complexity, 17(5):23-36 (2012).

2010

  • Galas, D.J., Nykter, M., Carter, G.W., Price, N. and Shmulevich, I., “Biological Information as Set-based Complexity,” IEEE Transactions on Information Theory, 56(2):667-677 (2010).
  • Auffray, C., Ideker, T., Galas, D.J., and Hood, L., “The hallmarks of cancer revisited through systems biology and network modeling” in Cancer Systems Biology, Bioinformatics and Medicine: Research and Clinical Applications (Ch 9), (eds. F. Marcus and A. Cesario), Springer Science & Business Media B.V. (2010).
  • del Sol, A., Balling, R., Hood, L., and Galas, D.J., “Diseases as network perturbations,” Current Opinions – Reviews, 21(4):566-571 (2010).
  • Wang, K., Lee, I., Carlson, G., Hood, L., and Galas, D.J., “Systems biology and the discovery of diagnostic biomarkers,” Disease Markers, 28(4):199-207 (2010).
  • Wang, K., Zhang, S., Weber, J., Baxter, D., and Galas, D.J., “Export of microRNAs and microRNA-protective protein by mammalian cells,” Nucleic Acids Research, 38(20):7248–7259 (2010)
  • Carter, G.W., Rush, C.G., Uygun, F., Sakhanenko, N.A., Galas, D.J., and Galitski, T., “A Systems-Biology Approach to Genetic Complexity:  Modular Analysis of Genetic-Interaction Networks,” Chaos, 20(2):026102 (2010).
  • Lee, L.W., Zhang, S., Etheridge, A., Ma, L., Martin, D., Galas, D.J., and Wang, K., “Complexity of the microRNA repertoire revealed by next generation sequencing,” RNA, 16:2170-2180 (2010).
  • Šípová, H., Zhang, S., Dudley, A.M., Galas, D.J., Wang, K., and Homola, J., “Surface Plasmon Resonance Biosensor for Rapid Label-Free Detection of Microrna at Subfemtomole Level," Analytical Chemistry, 82(24):10110–10115 (2010).
  • Weber, J.A., Baxter, D.H., Zhang, S., Huang, D.Y., Huang, K.H., Lee, M., Galas, D.J., and Wang, K., “The MicroRNA Spectrum in 12 Body Fluids,” Clinical Chemistry, 56:1733-1741 (2010).
  • Etheridge, A., Lee, I., Galas, D.J., and Wang, K., “Extracellular microRNA: a new source of biomarkers,” Invited review, Mutation Research, 717(1):85-90 (Dec 2010).
  • Wang, K., Zhang, S., Weber, J., Baxter, D., and Galas, D.J., “Mammalian cells in culture actively export specific microRNAs,” Nucleic Acids Research, 38(20):7248-7259 (2010).
  • Roach, J.C., Glusman, G., Smit, A.F.A., Huff, C.D., Hubley, R., Shannon, P.T., Rowen, L., Pant, K.P., Goodman, N., Bamshad, M., Shendure, J., Drmanac, R., Jorde, L.B., Hood, L., and Galas, D.J., “Analysis of Genetic Inheritance in a Family Quartet by Whole Genome Sequencing," Science, 328(5978):636-639 (2010).
  • Galas, D.J. and Sakhanenko, N., “Markov Logic Networks in the Analysis of Genetic Data,” Journal of Computational Biology, 17(11):1491-1508 (2010).
  • Moussay, E., Wang, K., Cho, J., van Moer, K., Pierson, S., Paggetti, J., Nazarov, P.V., Palissot, V., Hood, L., Berchem, G., and Galas, D.J., “microRNA as biomarkers and regulators in B chronic lymphocytic leukemia”, PNAS, 108(16):6573-6578 (2011).
  • Cho, J., Gelinas, R., Wang, K., Etheridge, A., Piper, M.G., Batte, K., Dakhallah, D., Price, J., Bornman, D., Zhang, S., Marsh, C., and Galas, D.J., “Systems biology of interstitial lung diseases: integration of mRNA and microRNA expression changes,” BMC Medical Genomics, 4:8 (2011).

2009

  • Nana-Sinkam, S. P., Hunter, M.G., Nuovo, G.J., Schmittgen, T.D., Gelinas, R., Galas, D.J., and Marsh, C.B., “Integrating the MicroRNome into the Study of Lung Disease,” Am J Respir Crit Care Med, 179(1):4-10 (2009).
  • Aebersold, R., Auffray, C., Baney, E., Barillot, E., Brazma, A., Brett, C., Brunak, S., Butte, A, Califano, A., Celis, J., Cufer, T., Ferrell, J., Galas, D., Gallahan, D., Gatenby, R., Goldbeter, A., Hace, N., Henney, A., Hood, L., Iyengar, R., Jackson, V., Kallioniemi, O., Kliingmüller, U., Kolar, P., Kolch, W., Kyriakopoulou, C., Laplace, F., Lehrach, H., Marcus, F., Matrisian, L., Nolan, G., Pelkmans, L., Potti, A., Sander, C., Seljak, M., Singer, D., Sorger, P., Stunnenberg, H., Superti-Furga, G., Uhlen, M., Vidal, M., Weinstein, J., Wigle, D., Williams, M., Wolkenhauer, O., Zhivotovsky, B., Zinovyev, A., and Zupan, B., “Report on EU-USA workshop: How Systems Biology Can Advance Cancer Research,” Molecular Oncology, 3:9-17, (2009).
  • Galas, D. J., and Hood, L., “Systems Biology and Emerging Technologies Will Catalyze the Transition from Reactive Medicine to Predictive, Personalized, Preventative and Participatory (P4) Medicine,”  Interdisciplinary Bio Central (ibc), Vol. 1, Number 2, Article No. 0006 (2009).
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