Galas Lab: Publications
New: Tetrad Detection Software for Yeast Genetics
February 26, 2019
In many eukaryotes, including the yeasts Saccharomyces cerevisiae, it is possible to recover all four of the haploid products of a single meiosis, tetrads. These tetrads can be characterized genetically and phenotypically. Tetrad analysis is a powerful technique that is routinely used to make associations between genetic variation and phenotype, uncover gene-gene interactions, and identify non-reciprocal meiotic recombination events (e.g. gene conversions).
Selected Major Publications for David Galas, PhD
Branscomb, E. W. and Galas, D. J., “Progressive Decrease in Protein Synthesis Accuracy Induced by Streptomycin in E. coli,” Nature, 254:161-163 (1975). (reprinted in Benchmark Papers in Genetics Series, Genes, Proteins and Cellular Aging, ed. R. Holliday, van Nostrand Reinhold Co., New York, (1976).
Galas, D. J. and Schmitz, A., “DNAase Footprinting: A Simple Method for the Detection of Protein-DNA Binding Specificity,” Nucleic Acids Res., 5:3157-3170 (1978).
2019 Publications from the Galas Lab
Sakhanenko, N.A., Galas, D.J., “Symmetries among multivariate information measures explored using Möbius operators”, Entropy, 21(1), 88; https://doi.org/10.3390/e21010088 (2019).
Uechi, L., Galas, D.J., Sakhanenko, N.A., “Multivariate analysis of data sets with missing values: an information theory-based reliability function”, J Comp Biol, 26(2), 152-171; https://doi.org/10.1089/cmb.2018.0179 (2019).
2018 Publications from the Galas Lab
Etheridge, A., Wang, K., Baxter, D., Galas, D.J., “Optimized protocol for preparation of small RNA NGS libraries from biofluids”, Chapter: Methods in Molecular Biology (2018).
Heintz-Buschart, A., Yusuf, D., Kayen, A., Etheridge, A., Fritz, J., May, P., de Beaufort, C., Upadhyaya, B., Ghosal, A., Galas, D.J., Wilmes, P., “Small RNA profiling of low biomass samples: identification and removal of contaminants”, BMC Biology, 16:52 https://doi.org/10.1186/s12915-018-0522-7 (2018).