View Google Scholar Profile for Dr. McLaughlin

Publications from the McLaughlin Lab:

Colón-Thillet R, Hsieh E, Graf L, McLaughlin RN Jr, Young JM, Kochs G, Emerman M, Malik HS. Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins. PLOS Biology 17(10): e3000181. (October 2019)

Sharma A, McLaughlin RN Jr, Basom RS, Kikawa C, OhAinle M, Yount JS. Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner. PLOS Pathogens 15(7): e1007925. (July 2019)

Lei Yang, Genevieve A. Metzger, Richard N. McLaughlin Jr, Characterization of LINE-1 transposons in a human genome at allelic resolution, bioRxiv 594200; doi: (April 2019)

McLaughlin RN Jr (2018) Reading the tea leaves: Dead transposon copies reveal novel host and transposon biology. PLOS Biology 16(3): e2005470. (March 2018)

McLaughlin RN JrHarmit S. Malik, Genetic conflicts: the usual suspects and beyond, (January 2017)

McLaughlin RN Jr, Gable JT, Wittkopp CJ, Emerman M, Malik HS. Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution. Mol Biol Evol. 2016 Aug;33(8):1889-901. doi: 10.1093/molbev/msw070. Epub 2016 Apr 6.

McLaughlin RN Jr, Malik HS. LINE-1 Retroelements Get ZAPped!. PLoS Genet. 2015 Jul;11(7):e1005364. doi: 10.1371/journal.pgen.1005364. eCollection 2015 Jul.

McLaughlin RN Jr, Young JM, Yang L, Neme R, Wichman HA, Malik HS. Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency. PLoS Genet. 2014 Sep;10(9):e1004531. doi: 10.1371/journal.pgen.1004531. eCollection 2014 Sep.

McLaughlin RN Jr, Poelwijk FJ, Raman A, Gosal WS, Ranganathan R. The spatial architecture of protein function and adaptation. Nature. 2012 Nov 1;491(7422):138-42. doi: 10.1038/nature11500. Epub 2012 Oct 7.

Reynolds KA, McLaughlin RN, Ranganathan R. Hot spots for allosteric regulation on protein surfaces. Cell. 2011 Dec 23;147(7):1564-75. doi: 10.1016/j.cell.2011.10.049. (December 2011)

PNRI is supported by

The SwedishTryskUSIPerkins CoieKnobbe MartensK L GatesLee & HayesAdaptive BiotechFirst PullSpecificaMatthew and Alayna Gagnier

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