Geneticists have long been taught that simple rules explain genetic inheritance. However, we now know that much of inherited disease risk falls outside these rules. In fact, current science can only account for a small amount of risk for inherited diseases.

The Nadeau lab studies disease conditions that break the usual rules of inheritance. Our research explores epigenetics, modifier genes, and phenotypic noise in testicular cancer and metabolic disease.

This pioneering work is unlocking the mysteries of inheritance in human health and disease.